I recommend staying near/in Dubrovnik and Split using Uber to get around.
To get from Dubrovnik to Split, we rented a car and had no problem driving the highway and stopping along the way. We divided the two larger cities with a stay in Korcula for a few nights, which I HIGHLY recommend.
Croatia is dotted with numerous wineries, from larger estates to those adjacent to the family home. It's fun to stop at the ones you just happen to see a small sign for along the way.
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